Should you give CBD to your cat? What the studies say (and don’t say)

Dr en Pharmacie

Joint pain, travel stress... CBD is increasingly being offered to cats, often based on the same promises as for dogs. But what do the studies say?

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An editorial and scientific team specialized in nutrition. Authors of the book Beneficial Foods (Mango Editions) and the podcast Food Revolutions.

The range of products has multiplied in recent years. Oil for an older cat’s osteoarthritis, a soothing paste before a trip in a carrier, a supplement for a particularly fearful cat, CBD is making its mark in the market for our feline companions.

A quick note: CBD (cannabidiol) is not THC (tetrahydrocannabinol), the psychoactive molecule in cannabis. Also extracted from hemp, CBD has no psychoactive effect, and it is credited with calming and pain-relieving properties, in humans as well as animals. 

The question remains what the studies in cats really say about it. How does it actually work in cats, and for which uses is the evidence solid?

📚 Read also | The best cat kibble, explained by a veterinarian

How does CBD work in cats?

Like dogs and humans, cats have an endocannabinoid system, a network of receptors (mainly CB1 and CB2) involved in regulating pain, inflammation, and stress.

CBD binds to it only weakly directly. It mainly acts indirectly by: 

  • slowing down the breakdown of endocannabinoids already present
  • binding to other receptors, especially those involved in pain perception

That is also why, because this action is diffuse, it is hard to predict the effects from one cat to another.

What do the studies actually show?

Arthritis: encouraging results, but a complicated trial

This is the strongest lead so far. A real-world study tested a CBD/CBDA-based paste in cats suffering from arthritis, in a 6-week crossover trial against placebo. 

The researchers observed a significant improvement in pain scores, assessed both by the owners and by the veterinarians.

But there is a caveat: of the 26 cats included, 54% dropped out of the trial, due to digestive issues or simply refusing the paste. So this is far from trivial: not only is the final sample very small, but it also reflects a difficulty in acceptance in cats.

Stress and transport: a result that does not go in the expected direction

On anxiety, contrary to what is often reported, the data are not favorable. A study conducted in 40 cats tested a single dose of CBD before crate transport followed by meeting an unfamiliar person, a real stress scenario. 

No significant difference was observed with placebo, neither in cortisol nor in observed behavior.

CBD for cats: what does the law say in France?

It is impossible to address the topic without this regulatory point: no CBD product intended for animals may claim a therapeutic effect in France, whether it is to relieve pain or calm a stressed cat. Only sale as a dietary supplement is authorized, never as a medicine.

Specifically, this also means that your veterinarian cannot prescribe CBD for your furry companion, since there is currently no authorized cannabidiol-based medication for animals. However, your veterinarian remains the right person to consult for information and help choosing the right option.

What dosage, and how quickly does it work?

There is no officially validated dosage for cats. Studies use doses of around 2 to 4 mg/kg, once or twice a day, but these cannot be directly applied to a commercial product, whose concentration varies greatly.

As for how long it takes to act, feline pharmacology data show a peak blood concentration around 2 hours after administration, a useful reference point but one that does not guarantee anything about the observed effect.

I would also advise against using a CBD oil designed for a dog or for a human on your cat: the concentration is not appropriate, and some human products contain excipients that are toxic to cats, such as xylitol.

Can CBD be dangerous for a cat?

The most common side effects remain mild: digestive upset, which appears to be the main area of concern in cats, and drowsiness at higher doses.

The real danger remains THC poisoning. Surprisingly, the most recent data suggest that cats metabolize THC differently from dogs and may be less neurologically sensitive to it than previously thought, as highlighted by the 2025 review

Of course, this in no way justifies taking that risk, and I strongly recommend that you never give a non-compliant product or one intended for humans. 

For caution, I would avoid CBD in kittens, pregnant or nursing queens, and cats suffering from liver failure, since CBD is metabolized by the same liver enzymes (cytochrome P450) as many medications.

How to choose a CBD oil for your cat

If you still want to try it, choose a product whose independent analysis certificate is available, with THC content below 0.2%, and a format your cat will actually accept: given the dropout rate observed in the osteoarthritis study, the best oil in the world is useless if your cat refuses it.

The feline data are encouraging for chronic pain, but remain much more uncertain for stress, and simply nonexistent for epilepsy. If in doubt, the ideal is to discuss it case by case with your veterinarian.


Sources and scientific studies

  1. Mulder LM, Deterd Oude Weme J, Blees NR, Wakshlag JJ, Hughes D, Corbee RJ (October 2025). “Field safety and efficacy study with a cannabidiol/cannabidiol acid-rich hemp paste in cats with osteoarthritic pain”,
  2. Weller JE, Flint HE, Hunt ABG, Ellerby Z, King T (November 4, 2024). “Investigating the effect a single dose of cannabidiol has on measures of stress in cats when being transported in a carrier and meeting a novel person in an unfamiliar environment”
  3. Cital SN, Wakshlag J, Kennedy A, Tittle D, Petty M (September 2025). “Cats and cannabinoids: past, present and future”, Journal of Feline Medicine and Surgery, vol. 27, no. 9.