Eggshell membrane: benefits, dosage, contraindications

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The eggshell membrane is a natural product containing, among other things, collagen, glucosamine, GAGs (glucosamine, chondroitin sulfate, hyaluronic acid) and keratin. The eggshell membrane has been shown to accelerate fibroblast cell division and to increase their metabolic activity by improving their collagen production. The eggshell membrane proves to be a valuable ally for skin and joint health. Its ability to reduce skin inflammatory processes is particularly noteworthy. The use of Ovoderm®, formulated from this membrane, has proven effective in significantly improving skin elasticity, even in individuals without prior skin alterations. Furthermore, Ovomet®, another formulation derived from the eggshell membrane, has demonstrated promising benefits in the treatment of arthritis in older adults, opening the way to new therapeutic perspectives.

Family or group: 

Superfood, Amino acids

Active ingredients:

Glucosamine

Collagen

Hyaluronic acid

Chondroitin


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Skin health
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Taking Ovoderm®, even for a short period and at a low dose, has demonstrated a notable improvement in the skin's protective function, strengthening its skin barrier. The results of a clinical study showed a significant increase in skin elasticity, accompanied by a visible reduction in skin fatigue and an increase in firmness. These benefits appear to be due to several factors: increased levels of collagen and hyaluronic acid, decreased activity of matrix metalloproteinases, inhibition of enzymes that degrade collagen (collagenase) and elastin (elastase), as well as a reduction in skin inflammation. Although the study observed a trend toward decreased skin pigmentation, this change did not reach statistical significance.

Posologie

posologieOral administration

posologie300 mg

formulationOvoderm


Wrinkles
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Ovoderm®, an innovative product based on eggshell membrane, is positioned as a promising solution in the fight against visible signs of skin aging, notably wrinkles. Its rich composition of natural ingredients such as collagen and hyaluronic acid makes it particularly effective at improving the health and appearance of the skin. nnClinical studies have shown that even short-term, low-dose consumption of Ovoderm® can strengthen the skin barrier, which is essential for maintaining skin hydration and protection.nn

Posologie

posologieOrally

posologie300 mg

formulationOvoderm


Arthritis
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A study examined the efficacy of daily administration of 300 mg of Ovomet® for the treatment of arthritis in elderly patients. The participants, suffering from diagnosed arthritis, took Ovomet® for 50 days. The study showed a significant reduction in joint pain and stiffness and an improvement in functional capacity from the start of treatment. At the end of treatment, the majority of patients experienced a significant improvement in pain and functionality. These results suggest that Ovomet® could be an effective natural alternative for managing pain caused by osteoarthritis, thereby improving quality of life.

Posologie

posologieOral administration

posologie300 mg

formulationOvomet


Joint pain
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Daily intake of 300 mg of Ovomet® for 50 days showed a positive effect on the linear stiffness of the Achilles tendon in elderly patients.

Posologie

posologieOral administration

posologie300 mg

formulationOvomet


Properties


Dermatological effect

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A study showed a significant improvement in skin barrier function, elasticity, firmness and skin fatigue following the consumption of a patented Ovoderm® extract. The study demonstrated that Ovoderm® can prevent and reduce the progressive loss of skin elasticity and firmness, characteristics of aging skin. These beneficial effects would be linked to the increase in collagen and hyaluronic acid levels, to the reduction of matrix metalloproteinase activity, and to the inhibition of skin inflammation.

Usages associés

Skin health, Wrinkles

Anti-inflammatory

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A study examined the impact of eggshell membrane hydrolysates on the activation of nuclear factor kappa B (NF-κB), a key component of the immune and inflammatory response. The results showed that these hydrolysates significantly activate NF-κB, suggesting a potential anti-inflammatory role. This mechanism could explain the beneficial effects observed in vivo, particularly in the context of inflammatory diseases such as arthritis.

Usages associés

Arthritis, joint pain


Safe dosage

Adult: 300 mg

Studies indicate a dose of 300 mg per day of the patented extract.