Best appetite suppressant supplement: a pharmacist’s opinion (2025)

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# Best appetite suppressant shake 🥇

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Nous avons analysé 16 compléments alimentaires vendus sur Internet selon 6 critères, et avons retenu ces 3 coupe-faim :

Meilleur complexe coupe-faim 🥇
> Coupe-Faim – Nutri&Co

Best natural appetite suppressant
> Psyllium Blond 99% organic – Amoseeds

Best konjac
> Konjac – Nutrimea

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Best appetite suppressant supplements

Our selection criteria

• Active ingredients: selection and quality of the active ingredients contained in the dietary supplement.
• Bioavailability: the form of the ingredients influences their absorption.
• Active ingredient concentration: an adequate level of active ingredients increases the product’s effectiveness.
• Presence of additives: flavorings, preservatives, and coating excipients.
• Price / day: this is the price per day of treatment at the brand’s recommended daily dose.
• Customer reviews: these customer reviews of the product are collected from the brand’s website, marketplaces, or review sites.

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Best appetite-suppressing complex 🥇

Nutri&Co’s appetite suppressant supplement is particularly effective because it contains DNF-10®, an innovative active ingredient obtained by hydrolysis of proteins from Saccharomyces cerevisiae.

It is one of the few active ingredients whose effectiveness has been tested in vivo (in humans). Two clinical studies totaling 84 subjects showed a reduction of 600 kcal per day in food intake after 8 weeks of treatment.

The two studies also showed a loss of 2 kg of body fat.

This supplement also contains carob, a plant known for its effect on satiety.

It is available online and in some pharmacies.

We like the Nutri&Co brand because it is reliable and transparent (read our full review here to learn more). We also note that customer reviews are very good.

This brand is based in Aix-en-Provence and places particular importance on the quality of the active ingredients in its products.

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Best natural appetite suppressant

The blond psyllium from Amoseeds comes from India. It is high quality: batches are filtered and sieved to ensure a maximum purity of 99 %, and a fiber concentration of 88 %. 

Organic, it does not contain ethylene oxide, a harmful pesticide used for sterilization, unfortunately found in some brands.

Amoseeds is a French brand specializing in superfoods and plant-based supplements.

The products are offered in raw form or as capsules and powders. They are organic, guaranteed additive-free and preservative-free.

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Best konjac

Nutrimea’s konjac-based supplement is concentrated at 90% in glucomannan fibers. These fibers can expand in the stomach when in contact with water, producing an immediate appetite-suppressing effect. 

The high glucomannan content allows you to fully benefit from the effectiveness of konjac.

Nutrimea is a brand that develops high-quality dietary supplements at controlled prices. All supplements are made in France, are gluten-free, lactose-free, and 100% natural. Some are certified organic. 

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How are our hunger and appetite regulated?

Signals from our body

Hunger is a message from the body that manifests as a hollow feeling in the stomach. 

It combines with appetite. Unlike hunger, which is a physiological need, appetite corresponds to the desire to eat and the pleasure derived from it.

Satiety, finally, represents the sensation of not being hungry; it is a signal from the body indicating that we have eaten enough. It is regulated by various hormones, notably leptin, a so-called anorexigenic hormone.

Disruptive factors

Factors can disrupt the signals: following a particular diet, periods of pregnancy or menstruation, certain medical conditions, or taking medications. 

The perception of hunger is then replaced by a desire to eat, linked to a need for reward, pleasure, or satisfaction. The sensation of satiety is no longer properly controlled, and snacking becomes more frequent. 

Should you take appetite suppressant dietary supplements?

Try eating differently first

Before considering appetite-suppressing supplements, I advise you to ask yourself about the cause of an excessive appetite, and about the specific solutions to adopt. 

Some issues require follow-up with a nutritionist, particularly in the case of a medical condition. It can be normal to have an increased appetite, for example during pregnancy, with the hormonal changes that occur.

To better feel food sensations, I invite you to eat slowly, in a calm setting, and to chew each bite thoroughly. 

Chewing, in addition to enabling better digestion, increases the feeling of satiety and helps naturally adjust food intake, thanks to the secretion of leptin.

 Avoid any other associated activity (no TV or phone), and avoid restrictive diets in favor of a balanced and varied diet.

Choose quality appetite suppressant supplements

Additionally, some active ingredients have a natural appetite-suppressing effect, and are found at concentrated dosages in dietary supplements.

Warning: some products may contain ingredients with adverse, sometimes serious, effects.

I strongly recommend choosing a quality product, taking short courses, and consulting a healthcare professional if in doubt.

Which active ingredients are the most effective?

Konjac

Konjac is a plant root. Rich in fiber and low in calories, it is a food known for its appetite-suppressing effect. 

The main fiber contained in konjac is called glucomannan. It is a soluble fiber that has the ability to absorb up to 100 times its volume in water.

Thus, these fibers clump together in the intestine and form a gel, which slows the absorption of nutrients. This triggers the feeling of satiety and limits snacking. 

This richness in fiber also makes it an ally for sluggish intestinal transit.

The effectiveness of konjac for weight loss is highlighted in this study: 83 overweight adults either consumed a konjac-based supplement dosed at 3 g of glucomannan fiber, or took a placebo. 

After 2 months, people taking konjac observed a significant reduction in their body weight, in fat mass, and in LDL cholesterol, the “bad” cholesterol. 

Carob 

Carob, or more precisely the fruit of the carob tree, contains numerous minerals, pectin (a gelling substance), proteins, and dietary fiber. Its seeds are particularly nutrient-dense.

This fruit exhibits antihyperlipidemic and antidiabetic effects, due to its high content of antioxidants and fiber. 

A double-blind clinical study, that is, compared to a placebo, over 6 weeks and with 58 volunteers, concluded a decrease in LDL cholesterol in the carob fiber group compared to placebo, and a decrease in triglycerides in women. 

A randomized trial, that is, compared with another treatment, observed a reduction in blood glucose (blood sugar levels) following the consumption of carob-based snacks before a meal, with an improved feeling of satiety. 

These beneficial effects of carob are promising. However, in my opinion, larger-scale studies are necessary to evaluate its effects on body weight and metabolism.

Psyllium

The psyllium is a plant with a mode of action equivalent to that of carob. Its seeds are rich in soluble fiber : they form a viscous gel in the stomach on contact with water, mechanically increasing the sense of satiety.

This clinical trial indicates that psyllium supplementation contributes to greater satiety and reduces appetite between meals, compared with placebo. 

In addition to its appetite-suppressing effect, psyllium may have a positive effect on the metabolic syndrome. This condition is characterized by abdominal obesity and abnormal blood sugar and lipid levels. This is shown by this review of studies published in 2018.

Fucus

Fucus is a brown seaweed, rich in minerals, vitamins, and iodine. 

This seaweed is made up of non-digestible mucilages, also called alginates: they swell quickly in the stomach and have the ability to prolong gastric emptying, to improve satiety, and to induce a reduction in food intake.

The high fiber content of fucus also promotes gastrointestinal health and the growth of a beneficial microbiota.

In a 2011 study, conducted as a double-blind trial (neither the doctor nor the patients knew who received the placebo or the active ingredient), it was reported that consumption of alginate-based beverages significantly increased the sense of satiety, reduced hunger, but did not have a direct effect on weight loss.

Side effects are rare, but fucus can interfere with normal thyroid function. I therefore advise against its use in cases of thyroid disorders. 

Green tea

Green tea leaves contain catechins, compounds rich in caffeine. The molecules mainly present in green tea are called EGCG (epigallocatechin gallate), and have powerful antioxidant properties. 

These EGCG may be able to increase thermogenesis and therefore energy expenditure, as shown by this study. EGCG could also exert anti-obesity effects by limiting the absorption and transport of lipids.

Caffeine

Caffeine is a bitter substance naturally present in many plants, including tea leaves, kola nuts, and cacao beans. 

It is best known and consumed for its positive effects on alertness and concentration, but it is frequently found among the ingredients of weight-loss supplements. 

Indeed, it has a diuretic effect (it helps the body eliminate excess salt and water through urine), and it stimulates metabolism.

A literature review revealed that caffeine, consumed half an hour to four hours before a meal, could influence appetite hormones and feelings of satiety. 

However, current data on the appetite-suppressing effect of caffeine remain contradictory, with other studies finding an increase in appetite following caffeine consumption!

These properties are also the cause of their side effects, especially in cases of excessive consumption: tremors, insomnia, palpitations.

In what form?

In capsules

The capsule form is the most commonly found form. Convenient to use, it allows an appropriate concentration of active ingredients, and limits the number of daily doses (when the product is of good quality). 

Konjac, fucus and green tea are generally packaged in capsules.

In powder and seeds

Lightly processed, high-quality powders or seeds allow an accurate dosing of active ingredients. 

This form is suitable for people who have difficulty swallowing capsules or who have swallowing disorders. 

Powders mix easily into a drink, water or fruit juice. But you can also add them to a yogurt or a protein shake.

Notably, psyllium and carob are available in this form.

In gummies

Gummies, or chewables, are a popular form because they resemble candy and are often flavored to improve the taste. 

It’s a form I rarely recommend, because gummies often contain many additives, sugar or sweeteners, which should be avoided when purchasing weight-loss and appetite-suppressant supplements.

As herbal tea and infusions

You can find fucus, mate, and, more generally, green tea consumed as infusions. 

Some formulations offer a blend of appetite-suppressing plants and diuretic and draining plants (hibiscus, ginger, lemon…).

The natural appetite-suppressing effect of water adds to that of plants: water takes up space in the stomach, causing a feeling of fullness.

Criteria to consider

1. Formulation

A sufficiently studied ingredient can be enough to exert an appetite-suppressing effect. This is the case with konjac, for example.

For it to be effective, I encourage you to check the actual content of active ingredients, and to choose a quality product. 

Mixing several ingredients can enable synergistic actions, depending on the product classes. You may find:

• some diuretic ingredients such as pilosella, dandelion, and field horsetail
• some actives that block fat absorption such as psyllium seeds and certain algae
• some actives that induce a feeling of satiety such as pectin, algae, and fucus

However, I advise you to be cautious when purchasing: the more active ingredients there are, the more the concentration of each tends to decrease. This impacts the final effectiveness of the dietary supplement.

If the product’s formula contains multiple active ingredients, limit yourself to 3 to 5 ingredients.

2. Concentration of active ingredients

The concentration of each ingredient, and of its active compounds, is important to ensure the effectiveness of a dietary supplement. 

For example, I recommend that you choose a konjac-based product containing a glucomannan content of at least 80% to exert a significant appetite-suppressing effect, with a daily intake of 3 grams spread throughout the day.

Moreover, a well-dosed formula prevents multiple doses, thereby improving long-term adherence. 

3. Production method

The way an ingredient is manufactured and packaged affects its final quality. Avoid intensive farming, prefer French laboratories and local or organic cultivation (French or at least European).

Organic certification largely ensures the absence of pesticides, and the control of raw materials.

4. Quality of the active ingredients

Choosing a good-quality dietary supplement is essential to optimize its effectiveness and avoid the occurrence of adverse effects.

For example, fucus, widely used in slimming products, can be contaminated with heavy metals, especially if the product is of poor quality. Over time it can cause sometimes serious kidney failure. I do not recommend using it long-term.

I invite you to check the origin of the ingredients, as well as the presence or absence of questionable additives. 

In addition to potentially being harmful to your long-term health, they can also cause side effects, particularly digestive ones (this is the case for certain texturizing agents like polysorbates). 

Generally, the longer the list of additives, the lower the quality of the product.

5. Price 

For ‘appetite-suppressing’ complexes combining multiple ingredients, or a single active ingredient concentrated enough like konjac or green tea, expect between €15 and €25 for a one-month course. 

Powdered or bulk forms generally offer better value for money.

For psyllium for example, a one-month course costs on average €10 to €15. For powdered green tea, the price varies widely; expect between €10 and €30 for a one-month course depending on the brand.

Precautions for use

Dietary supplements indicated to suppress appetite may contain a mixture of active ingredients. Each of them has its own precautions for use and contraindications.

I strongly recommend medical advice for people with a chronic illness, or if they are on concomitant medication. I advise against appetite suppressants for pregnant or breastfeeding women; indeed, some are contraindicated.

In summary

To be sure you choose a quality appetite suppressant supplement, check:

• 1. Product formulation: either a single concentrated ingredient, or a maximum of 3 to 5 actives per product
• 2. Concentration of active ingredients : a well-balanced formula with a sufficient level of active compounds
• 3. Production method : opt for non-intensive, local cultivation, preferably French and/or certified organic
• 4. Quality of active ingredients : check for the absence of controversial additives
• 5. Price : entre 15 and 25 euros per month of treatment for complexes and between 10 and 15 euros for powdered and bulk forms