GABA, gamma-aminobutyric acid, is a neurotransmitter found in the body. It plays an important role in brain activity and the nervous system.
Among its actions, it binds to inhibitory receptors in the brain (GABAA and GABAB receptors) and contributes to the regulation of your mood, stress, anxiety, and even insomnia symptoms. Its presence induces relaxation and a general calming effect.
Moreover, many therapies for anxiety and sleep problems, such as benzodiazepines (Alprazolam) and zolpidem, act by binding to the same receptors as GABA.
GABA is produced directly by the body from glutamine or glutamate, but can also be obtained through diet, or from dietary supplements. It is notably found in oilseeds (nuts), bananas, citrus fruits, and certain green vegetables.
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In cases of improper use or overdose
Taking GABA is generally safe for the healthy general population, provided it is used correctly!
Its improper use, or an overdose, could cause side effects. You may experience the following:
- experience skin tingling, or have redness on the skin
- be short of breath
- experience some digestive problems, such as nausea or abdominal pain
- be tired or be affected by drowsiness
- have dizziness and headaches
If any of these symptoms occur, stop taking GABA immediately and consult your primary care physician.
Contraindications to follow
Since GABA interacts with the central nervous system, it is contraindicated in certain situations. This is notably the case if:
- you are taking a sedative, anxiolytic, or antidepressant of the SSRI class to avoid creating drug interactions
- you have issues with blood pressure regulated by drug treatment
- you have a history of epileptic seizures
- if you are pregnant : GABA use has not been sufficiently tested
- if you are breastfeeding, to avoid transfer into breast milk
- in children
- In case of hypersensitivity to the molecule
