What is vitamin B12?
The vitamin B12 or “cobalamin” is a water-soluble vitamin. Within the body, it is involved in the process of cell division, the synthesis of proteins, and the construction of DNA.
It is also essential for the proper functioning of the nervous system and the formation of red blood cells.
It can be obtained through the diet and by consuming certain foods. Red meats and organ meats, seafood, fatty fish, eggs, and dairy products are good sources.
Taking a dietary supplement also helps meet daily requirements.
Read also | Choose the best vitamin B12
Vitamin B12 deficiency is common, especially among vegetarians, vegans, and those following plant-based diets. Indeed, this vitamin is mainly found in animal products.
Cobalamin deficiency also affects people over the age of 65.
Insufficient intake can cause inflammation and swelling in the joints. This then results in arthritic joint pain and cartilage wear.
What impact does it have on joint pain?
A deficiency can cause joint pain.
Most severe joint pains are caused by an injury or a chronic inflammation such as arthritis.
But a vitamin B12 deficiency can also be the cause.
Indeed, the latter causes an increase in the level of homocysteine, a sulfur-containing pro-inflammatory amino acid that accumulates in the blood. It is derived from methionine, which itself is synthesized by vitamin B12.
An excess of homocysteine (hyperhomocysteinemia) results in joint pain. It also reduces bone density and interferes with collagen production, essential for cartilage.
Finally, it increases the risk of osteoporosis, as shown by this study.
A sufficient intake of vitamin B12 is therefore important to maintain balanced homocysteine levels in the blood.

A deficiency accelerates cartilage wear.
A lack of vitamin B12 can accelerate wear and deterioration of the cartilage. Indeed, it causes inflammation, swelling, and friction in the joints.
These repeated frictions cause pain, gradually erode and weaken the cartilage. They increase the risk of rheumatoid arthritis.
As shown by this study, cobalamin may be useful in treating rheumatoid arthritis.

