Male fertility problems: the most effective dietary supplements

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Male infertility, defined as the inability to conceive after one year of unprotected intercourse, accounts for a significant portion of infertility cases worldwide. It affects about 9% of men aged 15 to 44 and is often linked to a decline in sperm quality, concentration, or motility. Causes are varied: infections, genetic abnormalities, hormonal imbalances, or poor lifestyle. The oxidative stress, resulting from the overproduction of free radicals, is particularly involved, as it can damage sperm DNA and impair their function.

Causes of male infertility

Male infertility often results from a combination of biological, environmental, and behavioral factors that compromise sperm production and quality. Among the main sources of identified toxicity, the use of certain medications is a crucial factor. For example, long-term treatments with antidepressants, analgesics, or steroids can disrupt testicular function. Sulfasalazine, a drug used for ulcerative colitis, is known to reduce sperm counts. Exposure to toxic environmental substances also amplifies the risks. Solvents, herbicides, dyes, heavy metals such as lead or mercury, as well as radiation, are major endocrine disruptors. Professionals working with these products are particularly vulnerable, and even past exposures can have persistent effects. These agents not only alter spermatogenesis but also promote oxidative stress. Lifestyle plays a decisive role. The use of recreational drugs such as marijuana and opioids (heroin) is associated with a significant decline in semen quality. Additionally, prior infections, notably mumps and sexually transmitted infections such as chlamydia and gonorrhea, can lead to obstructions or abnormalities of the genital tracts.

Treatments

To address this issue, natural plant-based treatments show promising results. Ashwagandha, for example, improves sperm parameters by increasing sperm count, motility, and morphology. Its antioxidant effect also protects cells against oxidative damage. Other plants, such as Tribulus terrestris, stimulate testosterone production, which is essential for spermatogenesis. Trace elements also play a key role. Zinc is crucial for hormone synthesis and sperm quality, while selenium acts as an antioxidant, reducing damage caused by oxidative stress. A diet rich in vitamins A, C, and E, combined with natural antioxidants like lycopene (found in tomatoes), promotes improvement in sperm parameters. Although these natural approaches are promising, they should be integrated into a comprehensive strategy including lifestyle changes, such as regular physical activity and stress reduction. These solutions, combined with appropriate medical care, offer hope for men facing infertility.

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Indications associées

Selenium deficiency

Zinc deficiency


Male fertility problems : les compléments alimentaires les plus étudiés


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Rather effective

Selenium

etudes3 studies
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Probably effective

Zinc

etudes2 studies

Vitamin E  plus Vitamin C  plus Selenium

etudes5 studies

Ashwagandha

etudes5 studies

Fenugreek

etudes3 studies
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Insufficient evidence

Astaxanthin

etudes1 study  

Lycopene

etudes1 study  

African plum

etudes2 studies

Nigella

etudes1 study  

Maca

etudes3 studies

Shilajit

etudes3 studies
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Traditionally recommended