Thyme: benefits, dosage, contraindications

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Thyme is an herb native to the Mediterranean region of Europe. It is also commonly cultivated in the Caribbean. The dried leaves and flowers contain the active principles, notably essential oils. Thyme contains 30 to 70% thymol, 3 to 15% carvacrol and several other constituents including borneol, geraniol, linalool and alpha-pinene. It also contains flavonoids, polyphenolic acids, triterpenic acids, as well as terpinene, tannins, saponins and other constituents. Numerous in vitro pharmacological studies conducted over the past decade have revealed well-defined pharmacological activities for both thyme essential oil and plant extracts. Thymus vulgaris oil is a mixture of monoterpenes, which act as antioxidants, antimicrobials and antispasmodics. The non-medicinal use of thyme deserves special attention, as thyme is used in the food and fragrance industries. It is widely used as a culinary ingredient and serves as a food preservative, notably because of its antioxidant effect. Therapeutically, thyme is used for coughs and ENT (ear, nose, and throat) infections.

Scientific name(s)

Thymus vulgaris

Family or group: 

Plants


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Bronchitis
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Oral intake of thyme, in combination with other herbs, appears to help improve symptoms associated with bronchitis. Indeed, some preliminary clinical evidence suggests that taking an herbal cough syrup containing thyme, anise, dried ivy leaf, and marshmallow root mucilage improves bronchitis symptoms, including cough and the amount of expectoration, compared with baseline symptoms in patients with bronchitis. In addition, taking 30 drops of thyme and primrose root extract five times a day for 7 to 9 days appears to reduce acute bronchitis symptoms and shorten the duration of bronchitis compared with placebo. In children and adolescents, preliminary clinical evidence suggests that taking a syrup containing thyme extract and ivy leaves for 10 days appears to help reduce symptoms, including coughing fits, in patients with acute bronchitis. The World Health Organization recognizes the use of thyme for coughs during colds or bronchitis. The usual dose is 1 to 2 g of dried plant per cup of boiling water, as an infusion, several times a day, or the equivalent in fresh herb.

Posologie

posologieBy mouth: leaf, aerial parts

posologie1 - 2 g

duration10 - days

formulationpowder, essential oil, tisane/tea/infusion, dry extract


Cough
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Clinical research suggests that thyme, in combination with rose hip, relieves the symptoms of bronchitis, including cough and fever, and increases the production of expectoration. nnThe European Medicines Agency (EMA) considers that thyme leaf / primrose root mixtures may claim either nn"well-established medicinal use for cough" (in the case of the expectorant properties of products that have received marketing authorization - MA), or "traditional use for cough associated with the common cold" when these are products without MA. nnIn addition, the World Health Organization (WHO) recognizes the use of thyme for cough during colds or bronchitis.nnThe usual dosage is 1 to 2 g of dried plant per cup of boiling water, as an infusion, several times a day, or the equivalent in fresh herb.nn

Posologie

posologieBy mouth: leaf, aerial parts

posologie1 - 2 g

formulationpowder, essential oil, tisane/tea/infusion, dry extract


Common cold
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The European Medicines Agency recognizes the traditional use of thyme as an expectorant, for cough and for the common cold. The World Health Organization recognizes the use of thyme for cough during colds or bronchitis, and as a gargle for laryngitis and inflammation of the tonsils.nnThe usual dosage is 1 to 2 g of dried plant per cup of boiling water, as an infusion, several times a day, or the equivalent in fresh herb.nnA thyme tea or a drop of essential oil diluted in a bowl of hot water can be used for inhalation to clear the airways. More concentrated infusions (5 g of dried plant for 100 ml of water) are used as a gargle or mouthwash.nn

Posologie

posologieOral use: leaf, aerial parts

posologie1 - 4 g

formulationpowder, tisane/tea/infusion, dry extract


Wound
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The application of a concentrated thyme infusion to wounds may disinfect them and promote healing. The World Health Organization recognizes the antiseptic and wound-healing properties of thyme when applied locally to superficial skin wounds and for mouth irritations.

Posologie

posologieTopical: leaf, aerial parts

posologie1 - 4 g

formulationpowder, herbal tea/tea/infusion, dry extract


Digestive disorders
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The World Health Organization recognizes the use of thyme for dyspepsia and other gastrointestinal disorders. The usual dosage is 1 to 2 g of dried plant per cup of boiling water, as an infusion, several times a day, or the equivalent in fresh herb.

Posologie

posologieOral: leaf, aerial parts

posologie1 - 4 g

formulationpowder, herbal tea/tea/infusion


Oral and dental infections
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Recent studies have shown the effectiveness of a varnish based on thymol and chlorhexidine (an antiseptic) applied at the base of the teeth for the prevention of cavities and gum disease. The World Health Organization recognizes the antiseptic and healing properties of thyme for topical application on superficial skin wounds and for mouth irritations.

Posologie

posologieBy mouth: leaf, aerial parts

posologie1 - 4 g

formulationessential oil, herbal tea/tea/infusion


Properties


Anti-inflammatory

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In vitro research shows that thyme extract may have anti-inflammatory activity. This effect is attributed to thyme's ability to scavenge nitric oxide radicals.

Usages associés

Bronchitis, common cold, oral and dental infections

Antioxidant

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Thyme and its constituents, thymol and carvacrol, may have antioxidant effects and protective effects on DNA. According to preliminary research, thyme's antioxidant effect may increase nitric oxide production and may help improve atherosclerosis and endothelial dysfunction.


Mucolytic

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In animals, thymol and carvacrol are able to facilitate the clearance of mucus from the airways. Moreover, a study of 60 patients with productive cough compared a five-day treatment with two different syrups, one based on thyme and the other based on bromhexine (a mucolytic). A comparable efficacy was observed between the two treatments.

Usages associés

Cough

Antimicrobial

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Preliminary research suggests that thyme has antimicrobial activity and modest antibacterial effects. It also appears to have antiviral activity against influenza A and respiratory syncytial virus. Other preliminary research suggests that thyme is active against fungi such as Candida albicans and other Candida species. Thymol is also active against fungal microorganisms that cause onychomycosis (nail infection). In vitro, thyme essential oil and thymol have an antiseptic action on germs such as Helicobacter pylori (responsible for duodenal ulcers).

Usages associés

Bronchitis, Common cold, Oral and dental infections

Antispasmodic

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In vitro research shows that thyme extract has antispasmodic effects. Flavonoids, one of thyme's active constituents, have antispasmodic activity that has been demonstrated in some animals.

Usages associés

Digestive disorders

Wound healing

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Thyme oil could improve the healing of burns by promoting the formation of new tissue.

Usages associés

Wound


Safe dosage

Adults 18 years and older: 1 g - 4 g (essential oil, herbal tea/tea/infusion)

The European Medicines Agency recommends the use of thyme in adults. There are no particular contraindications to the use of thyme. Adverse effects are rare. The usual dosage is 1 to 2 g of dried plant per cup of boiling water, as an infusion, several times a day, or the equivalent in fresh herb. A thyme infusion or one drop of essential oil diluted in a bowl of hot water can also be used for inhalation to clear the airways. More concentrated infusions (5 g of dry plant for 100 ml of water) are used as a gargle or mouthwash.

Children aged 12 to 18 years: 1 g - 2 g (essential oil, herbal tea/tea/infusion)

The European Medicines Agency recommends that the use of thyme be reserved for children older than twelve years.


Interactions

Médicaments

Antiplatelet agents/Anticoagulants: moderate interaction

Theoretically, thyme could have additive effects with anticoagulant or antiplatelet medications and possibly increase the risk of bleeding


Precautions

Pregnant women: avoid

Although studies have not shown toxicity to the fetus, it is preferable not to take thyme during pregnancy, except for culinary use.

Breastfeeding women: avoid

The active substances in thyme may pass into breast milk. Avoid using thyme while breastfeeding.

Allergies: avoid

The use of thyme is not recommended for people allergic to plants of the Lamiaceae family (mint, sage, rosemary, lavender, wild thyme ...).

Coagulation disorder: avoid

Thyme has antiplatelet effects and can cause bleeding or bruising if used in large amounts by people with coagulation disorders.