Sulfur: benefits, dosage, contraindications

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Sulfur is a chemical element essential for the proper functioning of the human body. As the third most abundant mineral in the human body after calcium and phosphorus, sulfur plays a crucial role in various physiological processes. Present in an amount of 1.6 g per kilogram of body weight, sulfur is essential to the integrity and elasticity of our tissues. It is notably a major constituent of amino acids such as methionine, cysteine and taurine, which are fundamental for protein synthesis. These proteins play a key role in the formation and maintenance of body tissues, including cartilage and arterial walls. Sulfur can be found in garlic, onions and broccoli. The risk of deficiency increases with aging. Historically, sulfur has been widely used in the treatment of various chronic conditions, notably osteoarticular disorders such as osteoarthritis and bronchial diseases. As a mucolytic agent, it helps reduce the viscosity of bronchial secretions, thereby facilitating their elimination. This property is also used in certain spa resorts, where sulfur-rich waters are used to treat skin, respiratory and rheumatic conditions. The role of sulfur extends to hepatic waste elimination processes, supporting the breakdown of physiological metabolites, steroid hormones and cholesterol. Additionally, it participates in the detoxification of toxic substances, including medications and xenobiotics. Oligotherapy products containing sulfur are used in the management of allergic conditions and in detoxification, and in the treatment of ENT conditions.

Family or group: 

Minerals and trace elements


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Acne
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Sulfur is an ingredient used in medicine in over-the-counter topical products intended to treat acne, at concentrations of 3% to 10%. Although data on its efficacy are mainly anecdotal, creams and ointments containing 1% to 10% sulfur have been used for decades, often in combination with other agents such as benzoyl peroxide or salicylic acid.

Posologie

posologieTopical application






Allergies
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A preliminary study indicates that a homeopathic nasal spray containing sulfur offers efficacy comparable to that of sodium cromoglycate nasal spray (an allergy medication) in relieving allergic rhinitis symptoms for 42 days.

Posologie

posologieIntranasal administration


ENT infections
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A preliminary study suggests that a homeopathic product containing sulfur relieves cold symptoms similarly to conventional remedies such as antihistamines, for up to two weeks.

Posologie

posologieOrally


Dermatoses
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Preliminary research shows that topical application of 10% sulfur can effectively reduce papules and pustules of rosacea compared with oral tetracycline treatment.

Posologie

posologieTopically


Chronic obstructive pulmonary disease
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Preliminary research indicates that inhalation of sulfurous water does not show improvement in lung function in patients with obstructive pulmonary disease after 12 days of treatment.

Posologie

posologieBy inhalation


Detoxification
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Sulfur plays an important role in the detoxification of heavy metals thanks to its compounds containing thiol groups, which are capable of binding these metals. This binding facilitates the excretion of metals, such as lead, mercury, and arsenic, thereby reducing their toxicity and accumulation in the body.

Posologie

posologieBy mouth


Properties


Dermatological effect

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Sulfur interacts directly with keratinocytes to transform into hydrogen sulfide by a mechanism not yet known. This compound helps break down keratin, exploiting its keratolytic action in the treatment of acne and seborrheic dermatitis.

Usages associés

Acne, Dermatoses

Antibacterial

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Sulfur shows activity against Propionibacterium acnes, a bacterium involved in acne. Its antimicrobial effects could result from its conversion into pentathionic acid (vitamin B5) by the normal skin flora or keratinocytes.

Usages associés

ENT infections

Respiratory effect

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Inhalation of sulfurous water is commonly used for respiratory disorders. Clinical evidence suggests that it may inhibit oxidative respiratory processes, offering a potential therapeutic benefit in the treatment of respiratory conditions.

Usages associés

Chronic obstructive pulmonary disease, Allergies


Safe dosage

Adult :

Topical products containing sulfur at concentrations up to 10% have been used safely for periods of up to 8 weeks. There is not enough reliable information available on the safety of using sulfur orally.


Precautions

Pregnant woman : use with caution

Topical products containing sulfur have been applied safely at concentrations up to 6% for periods of up to 6 days. Avoid oral use of sulfur due to a lack of reliable safety information.

Breastfeeding woman : use with caution

Topical products containing sulfur have been applied safely at concentrations up to 6% for periods of up to 6 days. Avoid oral use of sulfur due to a lack of reliable safety information.