Star anise: benefits, dosage, contraindications

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Star anise, also known as Chinese star anise, comes from the dried fruit of the tree Illicium verum, native to China and Vietnam. The fruit is a reddish-brown star, harvested and sun-dried to preserve its aniseed aroma. nnStar anise is primarily cultivated in China, where it has been used for centuries in cooking, traditional medicine, and religious rituals. Its varied uses include dried fruits, powders, and essential oils. First recorded in the classic Chinese herbalist Bencaogangmu during the Ming dynasty, star anise is described in the Chinese Pharmacopoeia as warming the yang, dispersing cold, regulating Qi, and relieving pain, notably abdominal colic and the common cold. The fruits or their powders are also used in traditional teas as sedatives and to treat agitation and insomnia. Its essential oil is mainly used for stomach ailments. nnThe star anise seed contains a volatile oil, of which 75% is anethole. Star anise also contains phenolic acids, including shikimic acid, famous for its role in the synthesis of oseltamivir, better known by the trade name Tamiflu. This antiviral drug is used to treat and prevent infections by influenza A and B viruses.nnStar anise is widely used as an expectorant to relieve respiratory problems such as cough, the common cold, and bronchitis. In addition, star anise is used as a carminative to relieve digestive disorders such as bloating, flatulence, and colic.nn

Other name(s) 

Badian

Scientific name(s)

Illicium verum

Family or group: 

Plants

Active ingredients:

Shikimic acid

Anethole

Estragole


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Digestive disorders, Flatulence
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In Chinese and Ayurvedic medicine, star anise is believed to improve digestion and to relieve symptoms of dysentery, dyspepsia, flatulence, and colic.nn

Posologie

posologieOral: fruit

posologie0.5 g

formulationinfusion


Cough, Flu
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Star anise, known for its medicinal virtues, is traditionally used in the treatment of symptoms of the flu and cough. Used mainly as an infusion, it warms the body, facilitating the dispersion of cold and the regulation of Qi, according to traditional Chinese medicine.nn

Posologie

posologieOral: fruit

posologie0.5 g

formulationinfusion


Autonomic dystonia
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Neurovegetative dystonia is a dysfunction of the autonomic nervous system, which is responsible for regulating involuntary bodily functions such as heart rate, digestion, pupil dilation, and temperature regulation. Star anise can provide symptomatic support in the management of neurovegetative dystonia thanks to its antispasmodic and soothing properties. It helps relieve muscle spasms and improves digestion by stimulating digestive secretions and reducing gas. In addition, its calming compounds can reduce anxiety and promote better sleep.

Posologie

posologieBy mouth: fruit

posologie0.5 g

formulationherbal tea


Properties


Hypoglycemic

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Star anise shows promising hypoglycemic properties, as demonstrated in an animal model of diabetes. Administration of an extract from the dried fruit for seven weeks reduced blood glucose, urea, and advanced glycation end product levels, while improving lipid profiles and liver function tests. In vitro, the extract inhibits the glycation of proteins and lipids, a phenomenon exacerbated by hyperglycemia and contributing to diabetic complications such as nephropathy, retinopathy, and neuropathy. The flavonoids and flavonols present in star anise combat glycation by neutralizing free radicals and chelating metal ions.


Antimicrobial

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A study by Minakshi De and colleagues found that star anise has antimicrobial properties, mainly attributable to anethole, an active component found in the dried fruit. Research has shown that star anise extract, particularly the alcoholic extract, is effective against a variety of microbes, including bacteria, yeasts, and fungi. Anethole isolated from the extract demonstrated inhibitory activity against the growth of Bacillus subtilis, Escherichia coli, and Saccharomyces cerevisiae.

Usages associés

Digestive disorders

Antiviral

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Although star anise contains shikimic acid, which is used as a raw material in the synthesis of the neuraminidase inhibitor oseltamivir (Tamiflu), there is no reliable evidence that star anise itself possesses antiviral activity.

Usages associés

Cough

Neurological

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Shikimic acid from star anise offers a neuroprotective effect against oxidative stress, potentially useful in neurodegenerative diseases. In addition, star anise acts as a potent inhibitor of acetylcholinesterase and butyrylcholinesterase, affirming its role as an anticholinesterase agent.nnFurthermore, inhalation of trans-anethole demonstrates a significant anxiolytic effect, suggesting potential sedative properties.nn

Usages associés

Autonomic dystonia


Safe dosage

Adult: 0.5 g - 3 g

- Dried fruit: infusion of 0.5 to 3 g for a cup of boiling water, at least 3 times a day, to be taken before and after meals. - Daily dose: 3 g; or essential oil: 0.3 g as a single dose. - Essential oil by inhalation. Star anise can be dangerous to health. In 2003, the FDA issued a warning against the consumption of star anise herbal teas because of severe neurological and gastrointestinal adverse effects. Products containing star anise associated with these symptoms are often contaminated with toxic Japanese star anise. However, high doses of star anise can also cause neurotoxicity. Avoid consuming large quantities of star anise.


Precautions

Surgical intervention: avoid

Contraindicated because of its anticoagulant effect.


Contraindications

Pregnant women: prohibited

Contraindicated for pregnant women.

Breastfeeding women: prohibited

Contraindicated for breastfeeding women.

Hormone-sensitive disease: prohibited

Contraindicated in cases of estrogen-dependent cancer.

Endometriosis: prohibited

Child up to 4 years old: prohibited

Star anise tea is a traditional remedy for infant colic, but it has been associated with undesirable neurological and gastrointestinal effects, including agitation, irritability, tachycardia, vomiting, diarrhea and epileptic seizures.