Plantain: benefits, dosage, contraindications

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Plantain is a perennial herbaceous plant widespread throughout Europe and temperate Asia, which grows on uncultivated and cultivated land. Its short roots bear rosette leaves; these broad, undivided leaves are used to soothe insect and nettle stings. Historically recognized for its medicinal properties, plantain was already used in Antiquity for its antihistamine and anti-infective effects, which are now confirmed by scientific studies. Plantain is rich in various bioactive components, including iridoids such as aucuboside, flavonoids, phenolic acids, and mucilages that contribute to its therapeutic effects. The leaves, mainly used in herbal medicine, must contain at least 0.5% aucuboside to ensure their efficacy. In herbal medicine, plantain is used in several forms: infusions, decoctions, in salads or as fresh juice to treat various ailments, such as inflammation of the mucous membranes or skin disorders. Plantain is often included in the composition of antitussive syrups sold in pharmacies.

Other name(s) 

Greater plantain

Scientific name(s)

Plantago lanceolata, Plantago major

Family or group: 

Plants

Active ingredients:

Iridoids

Phenolic acids

Mucilages

Tannins

Aucuboside


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Cough
✪✪✪✪

Plantain has traditionally been used to relieve dry cough thanks to its emollient properties. The mucilages contained in the leaves help soothe irritated mucous membranes of the respiratory tract, thereby reducing the frequency and intensity of coughing.

Posologie

posologieOral use: leaf

posologie2 - 4 g

formulationinfusion


Pharyngitis, Bronchitis
✪✪✪✪

For inflammations of the pharynx and mild bronchitis, plantain offers a soothing effect. Its components, notably iridoids such as acteoside, reduce inflammation.

Posologie

posologieOral use: leaf

posologie2 - 4 g

formulationinfusion


Gastritis
✪✪✪✪

Plantain has anti-inflammatory and emollient properties that can help relieve the symptoms of gastritis.

Posologie

posologieOral use: leaf

posologie2 - 4 g

formulationinfusion


Insect bites
✪✪✪✪

Thanks to its anti-inflammatory and antihistamine properties, plantain is effective against itching and irritation caused by insect bites. Topical application of the leaves or extracts can provide rapid relief

Posologie

posologieTopical use: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Acne
✪✪✪✪

The antibacterial properties of plantain help fight acne by reducing infection and inflammation. Topical application can help purify the skin and prevent breakouts.

Posologie

posologieTopical use: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Stomatitis
✪✪✪✪

Plantain offers benefits thanks to its healing and anti-inflammatory effects. Gargles or direct applications of plantain extracts can reduce pain and speed the healing of lesions.

Posologie

posologieOral use: leaf

posologie2 - 4 g

formulationpoultice, fluid extract


Properties


Antihistamine

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Plantain shows strong antihistamine activity, mainly due to its extracts that inhibit up to 80% of IgE antibody–mediated histamine release, which effectively helps reduce allergic reactions. This notable inhibition, observed even at low concentrations, supports its traditional use against allergies. In addition, plantain extracts also modulate inflammation by inhibiting key enzymes such as nitric oxide synthase and cyclooxygenases (COX-1 and COX-2) in macrophages. These properties, combined with bronchodilator effects, reinforce its role in treating allergic respiratory disorders.

Usages associés

Cough, insect bites

Antibacterial

full-leaffull-leafempty-leafempty-leaf

Plantain demonstrates strong antibacterial activity, thanks to compounds like aucuboside which is converted into a bactericidal dialdehyde. It is effective against a variety of pathogenic bacteria, including Staphylococcus aureus and Escherichia coli, making the plant useful in treating skin infections and other bacterial infections.

Usages associés

Acne

Anti-inflammatory

full-leaffull-leafempty-leafempty-leaf

Plantain shows significant anti-allergic and analgesic effects, reducing cough by 66%. It contains compounds such as acteoside and ursolic acid that inhibit the COX-2 enzyme, thereby reducing the production of inflammatory molecules. A plantain extract was able to reduce pro-inflammatory cytokines and improve the regulation of anti-inflammatory hormones in animal models.

Usages associés

Cough, Pharyngitis, Stomatitis

Digestive effect

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Plantain is beneficial for the digestive system thanks to its emollient and antispasmodic effects. The mucilages contained in the plant soothe irritated mucous membranes of the gastrointestinal tract, reducing inflammation and calming spasms, which helps relieve digestive disorders such as gastritis.

Usages associés

Gastritis

Wound-healing

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Plantain plays a notable role in wound healing, traditionally used for its beneficial effects on wounds. Its anti-inflammatory properties help alleviate symptoms such as redness, fever, swelling, and pain. An animal study demonstrated that the aqueous extract of plantain could effectively replace silver sulfadiazine, particularly at a 50% concentration, in the treatment of burns. Polyphenols, particularly plantamajoside, are recognized for their wound-healing virtues, facilitating the repair and regeneration of damaged tissue.

Usages associés

Acne

Gastroprotective

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Traditionally used to treat gastric ulcers, plantain shows significant efficacy in preventing and reducing ulcers. This activity is mainly attributed to the inhibition of acid secretion and the protective effect of its compounds on the gastric mucosa, thereby reducing inflammation and promoting the healing of ulcerated tissues.

Usages associés

Gastritis


Safe dosage

Adult:

- Dry powder: 3 g - Leaf infusion: 2 to 4 g of leaves for 150 mL of water brought to a boil then strained after 10 minutes. - Mother tincture: 3 times 75 to 100 drops per day. - Fresh juice: 1 to 2 teaspoons 2 to 3 times per day.


Contraindications

Pregnancy: contraindicated

Some data suggest that plantain affects uterine muscle tone.