Oregano: benefits, dosage, contraindications

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Oregano is a perennial herb in the Lamiaceae family, which also includes mint, thyme, marjoram, basil, sage, and lavender. Native to the warm temperate regions of Western Europe and the Mediterranean basin, oregano has spread widely and is now cultivated on most continents. The parts of oregano that are used are the leaves and the aerial parts. In cooking, the fresh or dried leaves are commonly used as a culinary herb, while for therapeutic uses its essential oil is widely used. Oregano essential oil is rich in volatile monoterpene phenols, notably carvacrol and thymol, which make up 70% to 85% of its content. These compounds are known for their powerful antibacterial and antifungal properties. Carvacrol, in particular, has been shown to be effective against various bacterial infections and can even enhance the effectiveness of antibiotics through a synergistic effect. The effectiveness of oregano is recognized for the symptomatic treatment of digestive disorders such as bloating, slow digestion, and flatulence, as well as for mild acute bronchial conditions. Oregano is also used for its beneficial effects on coughs related to ENT and bronchial conditions, febrile states, and colds.

Scientific name(s)

Origanum vulgare

Family or group: 

Plants

Active ingredients:

Carvacrol

Thymol


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Wound
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A small clinical trial shows that applying an ointment containing a 3% concentration of the water-soluble fraction of oregano twice daily for 10 to 14 days after a minor dermatological surgical procedure could reduce infection rates and improve scar formation compared with a petrolatum-based ointment. Oregano promotes the healing of minor skin inflammations and bruises, soothing damaged skin.

Posologie

posologieTopical use

posologie3%

formulationointment


Digestive disorders, Candidiasis
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Oregano is traditionally used to relieve mild gastrointestinal complaints, helping to improve digestion and reduce symptoms of discomfort, according to the EMA.

Posologie

posologieOral use

posologie500 mg

formulationpowder, essential oil


ENT infections, Bronchitis
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Oregano is recommended to ease cough associated with the common cold, helping to clear the airways, according to the EMA.

Posologie

posologieOral use

posologie500 mg

formulationpowder, essential oil


Properties


Antibacterial

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Oregano essential oil and its component, carvacrol, have significant antibacterial properties against a wide range of organisms, including antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus. Phenols such as carvacrol and thymol, present in oregano, accumulate in the bacterial cell membrane, disrupting its structure and function, which leads to leakage of potassium and phosphate ions, alters intracellular pH and depletes ATP, essential for bacterial survival. These effects make oregano a widely used remedy for combating infections.

Usages associés

Digestive disorders, ENT infections, wounds

Antifungal

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Oregano essential oil and its component, carvacrol, demonstrate antifungal properties by inhibiting the growth of several pathogens such as Aspergillus species, Candida albicans, and Trichophyton mentagrophytes. They block the germination and mycelial growth of Candida albicans, significantly increasing survival rates in infected mice.


Antiviral

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Carvacrol has shown antiviral activity against the H1N1 influenza virus in laboratory studies, although the concentrations required may be toxic to human cells.

Usages associés

ENT infections

Hormonal metabolism

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A study conducted on rats with polycystic ovary syndrome (PCOS) shows that oral administration of an oregano leaf extract at 250 or 500 mg/kg per day for 30 days indirectly increases fertility by improving markers associated with ovarian follicular development and the hormonal abnormalities seen in PCOS.


Safe dosage

Adults aged 12 years and older: 500 mg - 1000 mg (powder)

- Infusion: 4 to 6 g for 250 mL of boiling water, infuse 10 minutes, 3 times a day.nn- Encapsulated powder: 250 mg per capsule, 2 to 4 capsules per day.nn- Mother tincture (TM): 5 to 10 drops, 3 times a daynn

Child aged 7 to 12 years:

1 to 2 drops of essential oil.nn


Precautions

Breastfeeding women: avoid

Insufficient data.nn


Contraindications

Pregnant women: contraindicated

Oregano may have abortifacient and emmenagogue effects.nn