Lysine: benefits, dosage, contraindications
Other name(s)
L-lysine
Family or group:
Amino acids
Indications
Scoring methodology
EFSA approval.
Herpes ✪✪✪✪✪
Several clinical studies have shown that oral intake of lysine monohydrochloride at doses between 1,000 and 1,248 mg per day, or 1,000 mg three times a day, reduces the recurrence of herpes labialis infections compared with placebo. These results suggest that lysine could be an effective treatment to prevent outbreaks of herpes labialis (cold sores).
Posologie
Orally
1 - 3 g
Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis
Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride
Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis
Subjective response to lysine in the therapy of herpes simplex
Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis.
Clinical effectiveness of lysine in treating recurrent aphthous ulcers and herpes labialis
Sports performance ✪✪✪✪✪
During endurance exercise, lysine oxidation increases. People who regularly engage in physical activity generally require more protein to maintain optimal physical performance, although little data are available on this subject. Lysine supplements may be beneficial for athletes seeking to improve athletic performance and promote muscle recovery. Studies have shown that lysine supplementation can help reduce muscle breakdown and increase muscle protein synthesis after exercise, which can improve recovery and muscle growth. However, further research is needed to confirm these effects and to determine optimal lysine supplementation doses for athletes.
Posologie
Oral administration
4 - 6 g
The metabolic roles, pharmacology, and toxicology of lysine
Proteins and amino acids in postexercise recovery
Metabolic effects of the combination L-carnitine — L-lysine — methionine versus placebo during submaximal exercise
Emotional balance ✪✪✪✪✪
Studies have suggested that lysine consumption may help reduce stress, improve mood, and manage anxiety. Preliminary clinical research has shown that consuming lysine-enriched wheat reduces stress in women and anxiety in men in populations that typically consume cereal-based diets, compared with the control group. Although the underlying mechanisms are not yet fully understood, it has been suggested that lysine may affect the production of neurotransmitters such as serotonin, which play a key role in regulating mood and emotions.
Posologie
Oral
4 - 6 g
Osteoporosis ✪✪✪✪✪
Research has shown that lysine consumption may help increase bone density and reduce the risk of fractures in people with osteoporosis. Lysine promotes collagen synthesis, a protein essential to bone structure. Additionally, lysine plays an important role in calcium absorption, a mineral essential for bone health. Studies have shown that lysine supplementation can increase intestinal calcium absorption and reduce its urinary excretion, which may help prevent bone loss.
Posologie
Oral
400 - 800 mg
Properties
Metabolic
Lysine is an essential amino acid, one of the 20 building blocks of proteins. It plays a key role in the formation of collagen, bones, tendons, and blood vessels. Lysine also contributes to the production of enzymes, antibodies, and certain hormones needed for the growth and repair of tissues, particularly muscle tissue. Additionally, lysine supports optimal brain function by supplying nutrients necessary for the production of neurotransmitters such as serotonin, which regulates mood and emotions.
Usages associés
Musculoskeletal effects
Lysine is an essential amino acid that plays a key role in protein synthesis and muscle protection. By promoting protein synthesis and reducing protein breakdown, lysine helps preserve muscle mass and maintain strength and performance. In addition, lysine stimulates the production of growth hormones such as insulin and IGF-1, which are necessary to promote muscle growth. It also increases muscles' sensitivity to these hormones, which amplifies their anabolic effects. In addition to its beneficial effects on muscles, lysine is necessary for collagen synthesis and may therefore be important for bone health. Studies have shown that supplementation with calcium and L-lysine increases intestinal calcium absorption, while in vitro research has shown that lysine increases osteoblast cell proliferation.
Usages associés
Antiviral
Lysine is involved in inhibiting viral replication by specifically blocking the enzymes necessary for the synthesis of viral proteins. In vitro, lysine inhibits the growth of the herpes simplex virus.
Usages associés
Safe dosage
Adults 18 years and older: 1 g - 3 g
Lysine has been used at doses up to 6 grams per day for 8 weeks. It is most often used at doses up to 3 grams per day for a maximum of 1 year.
Plantes ou autres actifs
Lysine: moderate interaction
Pharmacokinetic research shows that taking lysine with calcium may increase calcium absorption.
Precautions
Breastfeeding women: avoid
Avoid the use of lysine due to insufficient information on its safety during breastfeeding.
Pregnant women: avoid
Avoid the use of lysine due to insufficient information on its safety during pregnancy.
