Juniper: benefits, dosage, contraindications

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Juniper is a shrub that grows wild in the mountainous regions of Europe. It bears fruit every two years; its berries are first green then turn dark blue-black at maturity. The famous alcoholic drink "gin" is obtained by distilling juniper berries. In herbal medicine, the berries as well as its essential oil are used. Juniper berries and leaves contain flavonoids, including apigenin, rutin and luteolin. Juniper berry oil is mainly composed of monoterpenes, including alpha-pinene (51.4%), myrcene (8.3%), sabinene (5.8%), limonene (5.1%) and beta-pinene (5.0%). The seeds and fruits also contain glycolic acid, formic acid, malic acid, acetic acid, ascorbic acid and camphor. Juniper extracts also contain potassium and phosphorus. Juniper is used for digestive problems, including flatulence, heartburn, bloating and loss of appetite. It is also used for urinary disorders. The young shoots are considered a remedy for the liver and the gallbladder. The essential oil is anti-inflammatory and is often recommended for joint and tendon problems.

Other name(s) 

Juniper berry, Common juniper

Scientific name(s)

Juniperus communis

Family or group: 

Plants

Active ingredients:

Flavonoids

Potassium

Apigenin

Rutin


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Digestive disorders
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In cases of dyspepsia, juniper acts on digestion and helps reduce flatulence and colic.

Posologie

posologieOral use: fruit, buds, leaf

formulationgemmotherapy, mother tincture, aqueous decoction


Urinary tract infections
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Juniper is highly recommended for cystitis.nnThe EMA indicates that the berries are used for minor urinary tract conditions.nn

Posologie

posologieOral use: fruit, buds, leaf

formulationgemmotherapy, mother tincture, aqueous decoction


Joint pain
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Juniper helps eliminate uric acid (uricosuric effect) and other toxins responsible for joint pain.nnThe essential oil is anti-inflammatory, and when applied topically it may relieve sprains, tendinitis and other musculoskeletal pains.nn

Posologie

posologieTopical, oral: fruit, buds, leaf

formulationessential oil, gemmotherapy, mother tincture


Liver disorders
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Thanks to its hepatoprotective properties, the young shoots of juniper are indicated for liver problems such as hepatitis, steatosis and cirrhosis.nn

Posologie

posologieOral use: buds, leaf

formulationgemmotherapy, mother tincture


Properties


Diuretic

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The diuretic action of juniper has been attributed to 4-terpineol. However, some animal research suggests that the diuretic effect is due in part to the essential oil and in part to hydrophilic constituents. nnThe significance of juniper's diuretic effects is unclear, because some animal studies show that juniper aqueous extract is no more effective than water at increasing urine volume, while other animal studies only show significant effects at higher concentrations.nn

Usages associés

Urinary tract infections

Antibacterial

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The juniper berry has demonstrated antibacterial effects in vitro. Juniper berries showed activity against E. coli, S. aureus, and H. alvei. A juniper leaf extract appears to have greater antibacterial activity than ethanol, methanol, and chloroform extracts.nn

Usages associés

Urinary tract infections

Analgesic

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Juniper appears to have some antinociceptive activity and probably acts both peripherally and centrally. nnIn animal research, a methanolic extract of juniper showed a dose-dependent effect on the writhing response. In addition, in mice, intravenous administration of a lyophilized aqueous juniper extract produced a 178% analgesic response, measured by thermal stimuli.nn

Usages associés

Joint pain

Anti-inflammatory

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The juniper fruit has been tested in the laboratory and was shown to be able to block the release of certain chemicals involved in inflammation, such as prostaglandins and a substance that activates blood platelets. When a juniper extract was given orally to rats, it significantly reduced paw swelling caused by a substance called carrageenan. In fact, the juniper extract decreased swelling by 60%, which is even more effective than indomethacin, an anti-inflammatory drug, which reduced swelling by 45% in that study.

Usages associés

Joint pain

Hepatoprotective

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Juniper has demonstrated hepatoprotective effects in animal research. Compared with rats receiving a placebo, rats receiving juniper and then exposed to CCl4 (a toxic agent) had less pronounced increases in serum levels of liver enzymes. Ethanol and aqueous extracts of juniper may be effective.

Usages associés

Liver disorders

Hypoglycemic

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In animals, juniper berries appear to reduce blood glucose. They act mainly by increasing peripheral glucose uptake.


Safe dosage

Adults aged 18 and over: 2 g (infusion, mother tincture, liquid extract)

Herbal tea: 2 g of the crushed or powdered plant material in boiling water as an infusion, 2-3 times a day.nnTincture: 1-2 ml 3 times a day.nnGemmotherapy: between 15 and 30 drops depending on the preparation.nn


Interactions

Médicaments

Antidiabetic medications: moderate interaction

Juniper may lower blood glucose (blood sugar). Taking juniper with antidiabetic medications may cause hypoglycemia. These antidiabetic drugs include: glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase) and others.

Diuretics: low interaction

Taking juniper with diuretics may cause excessive loss of body water. Excessive water loss can cause dizziness and an excessive drop in blood pressure. These diuretics include: chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide) and others.


Precautions

Breastfeeding: avoid

Safety during breastfeeding has not been established.nn

Children up to 18 years: avoid

Use in children and adolescents under 18 years of age has not been established due to a lack of adequate data. Avoid use.

Type 2 diabetes: use with caution

Juniper berries may lower blood glucose (blood sugar). They may cause hypoglycemia (abnormally low blood sugar) in people with diabetes. Use with caution.

Low blood pressure: use with caution

Juniper berries may affect blood pressure and complicate its control.


Contraindications

Pregnancy: contraindicated

Juniper's effects on the uterus may interfere with fertility or cause miscarriage. Juniper is not recommended for pregnant women or those trying to conceive.