Fermented papaya: benefits, dosage, contraindications
Other name(s)
Papaya
Scientific name(s)
Carica papaya
Family or group:
Plants
Indications
Scoring methodology
EFSA approval.
Healthy aging ✪✪✪✪✪
Fermented papaya is known for its anti-aging effects, largely thanks to its potent antioxidant properties. A clinical study demonstrated that daily intake of 9 grams of fermented papaya preparation for 4 weeks reduced oxidative damage to red blood cells, a key marker of oxidative stress. This effect theoretically contributes to preventing certain age-related degenerative diseases, such as neurodegenerative and cardiovascular diseases.
Posologie
Oral administration
3 - 9 g
Oxidative Stress in Patients with Alzheimer's Disease: Effect of Extracts of Fermented Papaya Powder
Skin health ✪✪✪✪✪
Fermented papaya is a valuable ally for skin regeneration and overall skin health. An open study showed that a dressing made from partially ripe papaya promoted healing of post-cesarean wounds, notably by accelerating the formation of granulation tissue.
Posologie
Oral
3 - 9 g
Immune support ✪✪✪✪✪
The immunomodulatory effects of fermented papaya are well documented. It can support the body in fighting infections and promote an optimal immune response, essential for maintaining health, particularly in immunocompromised or aging individuals.
Posologie
Oral
3 - 9 g
Hair loss ✪✪✪✪✪
Fermented papaya shows promising results against hair loss. A clinical study of 154 participants with alopecia found that a shampoo and lotion containing 2% fermented papaya significantly reduced hair loss while increasing hair density and hair shaft diameter. These effects are attributed to a reduction in oxidative stress on the scalp, stimulation of cellular energy in hair follicles, and a balance of the scalp microbiota.
Posologie
Topical, oral
3 - 9 g
Properties
Antioxidant
Fermented papaya is recognized for its powerful antioxidant effect, due to its ability to stimulate the body's endogenous defenses. Unlike conventional exogenous antioxidants, fermented papaya acts by increasing the endogenous production of glutathione and superoxide dismutase (SOD), two key enzymes that neutralize the free radicals responsible for cellular aging and degenerative diseases. nnA clinical study showed that a daily intake of 9 g for 4 weeks reduced oxidative damage to red blood cells, suggesting protection against aging and certain chronic conditions.nn
Usages associés
Immunostimulant
Fermented papaya also acts as a natural immunostimulant. In vitro studies have shown that it increases the synthesis of nitric oxide and the secretion of tumor necrosis factor (TNF-alpha) by macrophages. These actions strengthen the innate immune response. nn
Anti-inflammatory
Fermented papaya is distinguished by its notable anti-inflammatory action, largely due to its ability to modulate cytokine activity, those molecules that orchestrate the inflammatory response. According to studies, fermented papaya acts by regulating inflammatory pathways and reducing the expression of pro-inflammatory cytokines such as IL-1beta and IL-6, while stimulating anti-inflammatory cytokines such as IL-10. These effects have been particularly well documented in the context of chronic inflammatory conditions, such as periodontal diseases. Moreover, these effects are reinforced by the biochemical richness of fermented papaya, notably its content of essential amino acids, minerals, and vitamins, which support tissue repair processes and reduce damage associated with chronic inflammatory stress.
Usages associés
Safe dosage
Adult: 6 g - 9 g
The dosages of fermented papaya vary depending on the formulations and indications. For oral intake, clinical studies have used a dose of 9 grams per day for 4 weeks to demonstrate its antioxidant effects. For topical application, notably for skin care, products containing 2% fermented papaya have been used successfully, for example to reduce signs of skin aging or improve wound healing.
