Fucus: benefits, dosage, contraindications

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Fucus vesiculosus, or bladderwrack, is a brown seaweed from the cold waters of the ocean. This seaweed is particularly valued for its high iodine content, which is essential for thyroid health. It is also rich in polysaccharides such as fucoidan, known for its anti-inflammatory and anticoagulant properties. In addition to iodine, Fucus contains vitamins, notably B12, which is crucial for the nervous system, and minerals such as iron, supporting the formation of red blood cells.

Scientific name(s)

Fucus vesiculosus

Family or group: 

Aquatic organisms

Active ingredients:

Iodine

Calcium


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Metabolic syndrome
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Fucus vesiculosus, used in combination with other ingredients, shows potential in the management of metabolic syndrome. An observational study reported significant improvements such as reductions in weight, waist circumference, fasting glucose, and lipid and blood pressure markers. These results come from a product combining Fucus and Ascophyllum nodosum with chromium picolinate.

Posologie

posologieOrally

posologie500 mg

formulationInSea2®


Synergies


Obesity
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Clinical studies on the effectiveness of Fucus vesiculosus for weight loss in overweight or obese adults show mixed results. Although Fucus is used in combination formulations, no significant reduction in weight, body mass index, body fat, or markers of glycemic control was observed in treated groups compared with placebos. nnThese results suggest that, although Fucus is promoted for its weight-management properties, its effectiveness is unproven.nn

Posologie

posologieOral administration

posologie500 mg

formulationstandardized extract


Iodine deficiency
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Although Fucus vesiculosus is a rich source of iodine, reliable evidence is lacking regarding its specific clinical effects for treating iodine deficiency. Historically used to correct deficiencies and prevent goiter, current research on its effectiveness alone is insufficient.nnAccording to the French Agency for Food, Environmental and Occupational Health & Safety (ANSES), the iodine content of fucus (Fucus vesiculosus) varies considerably depending on the environment in which it grows, the season, the age of the plant and the part used. However, on average, a 5 g portion of dried fucus contains about 450 micrograms of iodine.nn

Posologie

posologieOral administration

posologie500 mg

formulationstandardized extract


Properties


Metabolic

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Fucus vesiculosus is rich in fucoxanthin, which can stimulate thermogenesis in adipose tissue, increasing heat production and fat burning. This action may be useful for promoting weight loss and managing obesity.

Usages associés

Obesity, metabolic syndrome

Antiplatelet agents/Anticoagulant

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Fucoidan, a sulfated polysaccharide from Fucus vesiculosus, shows anticoagulant effects in laboratory studies, acting on platelet adhesion and promoting fibrinolysis. However, its intestinal absorption is low, limiting its anticoagulant activity in humans.


Hypoglycemic

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Preliminary research indicates that Fucus vesiculosus extract may reduce postprandial insulin by inhibiting key digestive enzymes, without significantly affecting glucose levels, suggesting potential to help manage insulin without directly impacting blood sugar levels.

Usages associés

Metabolic syndrome

Dermatological effect

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Topically applied Fucus vesiculosus can reduce skin thickness and signs of aging by increasing the expression of cell integrins. It also stimulates fibroblasts via transforming growth factor, thus aiding wound healing.


Safe dosage

Adult :

Studies indicate a dosage of 500 mg to 2000 mg.nnOral consumption of Fucus vesiculosus can be dangerous due to its iodine and heavy metal content. Fucus vesiculosus contains up to 0.05% iodine, i.e., 226 mcg per gram of dry weight. Ingesting more than 150 mcg of iodine per day can cause hyperthyroidism or worsen existing hyperthyroidism. Furthermore, Fucus vesiculosus may contain heavy metals such as cadmium, arsenic, and lead, and may cause heavy metal nephropathy. nn


Precautions

Pregnant: avoid

Pregnant and breastfeeding women should avoid consuming Fucus vesiculosus due to its heavy metal content.nn

Breastfeeding: avoid

Pregnant and breastfeeding women should avoid consuming Fucus vesiculosus due to its heavy metal content.nn


Contraindications

Thyroid disorders: contraindicated

Fucus vesiculosus contains significant amounts of iodine, and excess iodine can worsen thyroid disorders. Prolonged use or excessive amounts of iodides can cause or exacerbate thyroid gland hyperplasia, thyroid adenoma, goiter, and hypothyroidism. nn