Glutinous alder: benefits, dosage, contraindications
Other name(s)
Black alder, sticky alder, verne, vergne
Scientific name(s)
Alnus glutinosa, Betula glutinosa, Alnus barbata
Family or group:
Plants
Active ingredients:
Tannins
Lignans
Polyphenols
Flavonoids
Anthraquinones
Indications
Scoring methodology
EFSA approval.
Venous thromboses ✪✪✪✪✪
Black alder buds are used for venous inflammatory conditions. They are indicated in the prevention of phlebitis and thromboses.nn
Posologie
Oral: buds
gemmotherapy
ENT infections ✪✪✪✪✪
Black alder is used in the respiratory tract as an anti-inflammatory: rhinitis, sinusitis, bronchitis, and all chronic lung diseases.nn
Posologie
Oral: buds, bark, leaves
hydroalcoholic extract, gemmotherapy
Stomatitis ✪✪✪✪✪
A decoction of black alder bark is used to treat swellings and inflammations originating from mucous tissues. It is therefore recommended for the treatment of sore throats and pharyngitis.
Posologie
Oral use: buds, bark, leaves
hydroalcoholic extract, gemmotherapy
Rheumatism ✪✪✪✪✪
Traditional use: treatment of pain related to rheumatism.
Posologie
Oral use: bark, leaves
30 g
hydroalcoholic extract
Cognitive decline ✪✪✪✪✪
The alder bud has a beneficial effect on the arterial capillary network that supplies the brain and central nervous system. Traditionally prescribed to strengthen memory in seniors, at a dose of 50 to 60 drops in 1DH over 4 months.
Posologie
Oral use: buds
gemmotherapy
Migraine ✪✪✪✪✪
Traditionally recommended for migraine attacks. 30 drops in 1DH, every 2 hours during the acute phase.
Posologie
Oral use: buds
gemmotherapy
Properties
Anti-inflammatory
The diarylheptanoids and phenolic glycosides isolated from A.glutinosa have shown significant anti-inflammatory effects. Among them, oregonin and hirsutenone were particularly effective at reducing the production of NO (nitric oxide) and COX-2, two substances involved in inflammatory processes.nnOregonin also has other anti-inflammatory effects. It inhibits the production of the enzyme iNOS (inducible nitric oxide synthase) by reducing the activity of certain transcription factors (NF-κB and AP-1) that control the production of inflammatory molecules. In addition, oregonin decreases lipid accumulation, inflammation, and the production of ROS (reactive oxygen species) in human macrophages, which confirms its anti-inflammatory action.nnThese findings suggest that these components could be useful for preventing and treating atherosclerosis, a disease linked to inflammation of blood vessels, by limiting NF-κB activation.nn
Usages associés
Antioxidant
Numerous reports indicate that extracts and compounds isolated from this genus (Alnus) have significant antioxidant activity. It has been reported that oregonin and hirsutenone have shown a strong ability to scavenge oxygen radicals. In addition, the antioxidant properties of black alder extract are linked to an effective reduction of inflammatory processes.nn
Anticancer
A leaf extract of black alder showed activity against cervical and prostate adenocarcinoma cells in vitro. Hirsutanone, isolated from black alder leaves, demonstrated activity against human colon cancer cells in vitro. The mechanism of action is attributed to the induction of oxidative stress and topoisomerase II, causing DNA strand breaks that lead to cell death. However, other diarylheptanoid compounds isolated from the bark appear to reduce oxidative stress by decreasing the production of reactive oxygen species (ROS) and by increasing the expression of enzymes involved in ROS elimination. The effects of diarylheptanoids on cancer cells may be dose-dependent.
Antimicrobial
Ethanolic leaf extracts of Alnus species showed antimicrobial activity against E. coli, B. subtilis, P. aeruginosa, S. aureus, C.albicans. Compounds isolated from the extract, oregonine and hirsutanone, were also evaluated for their antibacterial activities and were found to be active against MRSA strains (S. aureus methicillin-resistant).
Usages associés
Hepatoprotective
Researchers Buniatian et al. examined how an ellagitannin-based preparation, extracted from the cones of the black alder, could protect the liver. They tested this extract on acute liver lesions caused by carbon tetrachloride, a chemical toxic to the liver. They found that this extract had a protective effect on the liver even at a very low dose (1 mg/kg), which is ten times lower than the dose usually used for traditional flavonoid-based medicines.nnThe compounds present in black alder help limit problems related to bile production, have an anti-inflammatory effect, stabilize cell membranes, and help restore the physiological antioxidant system.nn
Safe dosage
Adults aged 16 and over: 30 g - 50 g
Adult/adolescent - mother tincture : 5 drops 2 to 3 times per day in a glass of water. nnDilution 1D : 50 drops 2 to 3 times per day in a glass of water.nnInfusion: 30 to 50 g of leaves per liter of boiling water. Bring to a boil for 5 minutes, then remove from heat and let steep for one hour.nn
Child aged 6 to 16 years:
Child (from 6 years old) - mother tincture : 1 drop per 10 kg in a glass of hot water, once a day. nnDilution 1D : 5 drops per year of age, or 1 drop/kg/day, in a glass of hot water.nn
Interactions
Médicaments
Cisplatin: low interaction
Laboratory research shows that black alder bark extracts may interact with the chemotherapeutic effects of cisplatin. This interaction has not been evaluated in humans.
Doxorubicin: low interaction
Laboratory research shows that black alder bark extracts may interact with the chemotherapeutic effects of doxorubicin. This interaction has not been evaluated in humans.
Precautions
Pregnant women: avoid
Due to lack of information, avoid use or consult your therapist.nn
Breastfeeding women: avoid
Due to lack of information, avoid use or consult your therapist.nn
