Arnica: benefits, dosage, contraindications

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Native to the mountainous regions of Europe, Arnica is a perennial plant well known in phytotherapy. Its bright yellow flowers tending toward orange and resembling daisies grow in alpine meadows on acidic, well-drained soils. Arnica is used in phytotherapy and homeopathy to treat minor injuries. However, its popularity has led to overharvesting, threatening its availability in the wild. Today, Arnica is subject to strict regulations to ensure its preservation. Whole flower heads, or arnica flowers, are the main parts used therapeutically. Harvested by hand during flowering, they can be used fresh or dried. Arnica is available in phytotherapy in the form of tinctures, creams, gels, and vegetable oils. The effectiveness of Arnica is due to its active components, notably sesquiterpene lactones such as helenalin, which have powerful anti-inflammatory properties. It also contains flavonoids and derivatives of caffeic acid, enhancing its antioxidant and healing effects. Traditionally used to treat bruises, sprains, and muscle pain thanks to its analgesic and anti-inflammatory properties, Arnica is also recommended clinically to reduce edema and postoperative pain, as well as to treat various inflammatory skin conditions.

Other name(s) 

The Gold of the Vosges

Scientific name(s)

Arnica montana

Family or group: 

Plants

Active ingredients:

Helenalin tiglate

Dihydrohelenalin


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Rheumatism
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Within the treatment of rheumatic manifestations, Arnica has been the subject of several clinical studies aimed at evaluating its efficacy. An open clinical trial showed that the application of an arnica gel (A. Vogel Arnica Gel) twice a day for three weeks in people suffering from osteoarthritis reduced the total symptom scores, including pain, stiffness and functional limitation, compared with baseline measurements. A larger randomized clinical trial found that the application of the same gel was as effective as ibuprofen in reducing pain intensity and improving hand function. ESCOP recommends arnica flowers for external use in the symptomatic treatment of rheumatism.

Posologie

posologieTopical use: flower

posologie50%

formulationgel, cream, oil


Sprain, Contusion, Bruises
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Arnica is widely used in minor trauma, that is, in cases of non-open skin injury such as contusions, bruises, sprains, strains, or others. According to ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for these indications. Its efficacy is based on traditional use. In clinical practice, Arnica shows promising potential in relieving postoperative symptoms and pain associated with trauma. Although some clinical studies suggest that topical products containing 10% Arnica, as well as oral homeopathic products, do not effectively reduce postoperative bruising, conflicting research highlights their benefits. For example, one study showed that applying a 20% Arnica ointment twice daily for two weeks reduced laser-induced bruising compared with a plain white petroleum jelly ointment. Similarly, a specific Arnica cream, applied four times daily, reduced periocular bruising in the first week after rhinoplasty compared with no local treatment. Furthermore, the use of a specific oral homeopathic Arnica product demonstrated a reduction in bruising in women undergoing facelift surgery compared with placebo on postoperative days 1 and 7. A more recent clinical study examined the effect of topical application of Arnica or mucopolysaccharide polysulfate (MPSP) following lower wisdom tooth extraction. Results showed that the Arnica and MPSP groups experienced less pain than the control group up to the fifth day. Arnica was more effective at reducing trismus, while MPSP was more effective at decreasing edema.

Posologie

posologieTopical: flower

posologie10 - 20%

formulationgel, cream, oil


Muscle pain
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According to ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for its use in the treatment of localized muscle pain. The effectiveness of Arnica in relieving muscle pain has been explored across several clinical studies, however the results remain contradictory. nnIn one of the studies, the topical application of a 7% arnica cream did not show a significant reduction in muscle pain following calf-strengthening exercises. Another study revealed that although arnica applied immediately after intense exercise did not influence performance or markers of muscle damage, it potentially reduced muscle tenderness three days later. Finally, a study evaluating the effect of a mud poultice containing arnica and menthol indicated an accelerated recovery of strength and a significant reduction in muscle pain after intensive training sessions, although with no impact on muscle morphology.nn

Posologie

posologieTopical use: flower

posologie7 - 50%

formulationgel, cream, oil


Varicosities
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A randomized double-blind study compared the topical application of a cream containing arnica flower extract to a placebo in patients suffering from chronic venous insufficiency (primary varicose veins of the legs). After three weeks of treatment, combined with basic hydrotherapy, there was a significantly greater improvement in the group that received the arnica-based treatment.nnHowever, another study, including 100 patients divided into two groups of 50 each to receive either a gel of arnica flower extract or a placebo, found comparable improvements in both groups, with no significant difference between them.nn

Posologie

posologieTopical use: flower

formulationgel, cream, oil


Gingivitis, Canker sores
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According to ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for its anti-inflammatory properties useful against gingivitis and canker sores.nnThe arnica product should not be swallowed. Local application or gargle.nn

Posologie

posologieOral use: flower

formulationgel, infusion, mother tincture


Insect bites
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According to ESCOP (European Scientific Cooperative on Phytotherapy) and the EMA (European Medicines Agency), Arnica is recognized for its anti-inflammatory properties useful against certain skin inflammations, including insect bites.nn

Posologie

posologieTopical use: flower

formulationgel, cream, oil


Properties


Anti-inflammatory

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The efficacy of Arnica against inflammation can be explained by the action of specific components such as helenalin. Research has shown that helenalin has significant anti-inflammatory properties, demonstrated by its ability to inhibit carrageenan-induced edema in rats in several animal model experiments. In addition to helenalin, Arnica contains sesquiterpene lactones, which act at the cellular level to inhibit the processes responsible for the initiation of inflammation. Thus, they block the activation of nuclear factor kappa B (NF-κB), a protein essential to the triggering of the inflammatory response, which prevents the excessive production of molecules and enzymes that promote inflammation, such as pro-inflammatory cytokines, cyclooxygenase-2 (COX-2) and nitric oxide synthase.

Usages associés

Rheumatism, Sprain, Gingivitis, Varicose veins

Analgesic

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A study has shown that sesquiterpene lactones, including helenalin found in Arnica, act as anti-inflammatory agents by inhibiting several biological pathways responsible for inflammation and pain, in particular the migration of polymorphonuclear neutrophils (white blood cells) to the site of injury. These anti-inflammatory actions could contribute to their analgesic effects.

Usages associés

Rheumatism, sprain, muscle pain, varicosities, insect bites


Safe dosage

Adult: 20% - 25% (mother tincture)

Arnica is used in various topical formulations, notably as a gel, cream, ointment, oil, and dressing. For mouthwashes a 10% diluted tincture is used. Arnica is not recommended for oral use or for topical application on an open wound.


Precautions

Adults: use with caution

For oral use only homeopathic preparations are permitted. Ingesting Arnica in any other form causes cardiotoxicity and serious side effects.


Contraindications

Pregnant women: contraindicated

Arnica is contraindicated for topical or oral use.

Breastfeeding women: contraindicated

Arnica is contraindicated for topical or oral use.

Allergies: contraindicated

Arnica can trigger immune reactions in people allergic to other plants in the Asteraceae family. Members of this family include chrysanthemums, marigolds, daisies, and many other plants.