Caraway: benefits, dosage, contraindications

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Caraway is a biennial plant cultivated mainly for its seeds, prized for their aromatic flavor in cooking. Traditionally, these seeds are used for their carminative and appetite-stimulating properties and also to stimulate lactation, similar to anise. The caraway fruit used in therapeutics must contain at least 30 ml/kg of essential oil to be effective. This yellow-green essential oil, present at 3 to 7% in the fruit, is composed mainly of carvone (50-65%) and limonene (up to 45%), with less than 1.5% carveol and dihydrocarveol. The fruit also contains 10 to 18% vegetable oil, rich in petroselinic acid (30-43%), linoleic (34-37%), oleic (15-25%) and palmitic (4-5%). Other constituents of caraway include about 20% protein, 15% carbohydrates, phenolic acids—mainly caffeic acid—as well as traces of flavonoids such as quercetin, kaempferol and their glycosides. Caraway seeds are recommended to relieve spasmodic gastrointestinal disorders such as flatulence and bloating, and are particularly advised for infant colic.

Scientific name(s)

Carum carvi

Family or group: 

Plants

Active ingredients:

Carvone

Carveol

Limonene


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Flatulence, Digestive disorders
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Caraway is frequently used in combination with peppermint to alleviate the symptoms of dyspepsia. Clinical studies and a meta-analysis show that consumption of a combination of 50 mg caraway oil and 90 mg peppermint oil, administered 1 to 3 times per day for 4 weeks, improves quality of life and reduces symptoms such as a feeling of fullness, pain, and mild gastrointestinal spasms. This combination would be as effective as cisapride in relieving dyspepsia and improving postprandial distress syndrome and epigastric pain. Another combination including caraway, peppermint, German chamomile and other herbs, taken at 1 mL three times daily for 4 weeks, showed a significant reduction in symptoms such as acid reflux, epigastric pain, cramps, nausea and vomiting. These results suggest that caraway, used with other herbs, could be beneficial for treating dyspepsia.

Posologie

posologieOral: seed

posologie50 mg

duration4 - weeks

formulationinfusion, Carmenthin®, dry extract


Synergies


Digestive spasms
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According to ESCOP, caraway is recommended for spasmodic gastrointestinal disorders such as flatulence and bloating.

Posologie

posologieOral: seed

posologie1.5 - 6 g

formulationinfusion, Carmenthin®, dry extract


Infant colic
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According to ESCOP, caraway is recommended for flatulent colic in infants.

Posologie

posologieOral: seed

posologie1 - 4 g

formulationpowder, infusion


Lactation
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Caraway, traditionally used as a galactagogue to stimulate lactation, does not have strong clinical evidence supporting this use. Studies note the presence of components such as carvone in breast milk after consumption, although they do not demonstrate a significant effect on milk production. Some research suggests a possible increased acceptance of flavors by breastfed infants exposed to these dietary components.

Posologie

posologieOral: seed

posologie1.5 - 6 g

formulationpowder, infusion


Properties


Digestive effect

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Caraway essential oil locally stimulates the gastric mucosa, which activates the vagus nerve, resulting in increased tone and rhythmic contractions of the stomach. This action promotes the expulsion of air from the stomach and increases gastric secretion, thereby providing beneficial effects in the management of digestive disorders such as flatulence and bloating sensations. In addition, caraway may also positively influence bile flow, reinforcing its role in facilitating digestion.

Usages associés

Flatulence, infant colic

Antimicrobial

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Cell culture studies show that caraway extracts and oil have antibacterial activity against numerous organisms, including Bacillus cereus, Escherichia coli, and Staphylococcus aureus. Caraway essential oil is more active against gram-positive bacteria than against gram-negative bacteria. Furthermore, the oil has shown significant antifungal and anti-Candida effects, with retention of its efficacy after gamma irradiation, indicating stability of the active components. These properties suggest a potential use for caraway in antimicrobial applications, with a positive correlation between the oil's limonene content and its antibacterial activity.


Antispasmodic

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One study explored the effects of Carum carvi (caraway) extract on intestinal smooth muscle cells from guinea pigs. The main observed mechanism of action was a reduction in the muscle cells' response to acetylcholine (ACh), a neurotransmitter that induces muscle contraction. The caraway extract showed a relaxing effect on smooth muscle cells, demonstrating a dose-dependent inhibition of ACh-induced contraction. At the highest concentration tested (2.5 mg/mL), the extract markedly inhibited the contractile response of the muscle cells to ACh, which could partly explain caraway's effectiveness in relieving gastrointestinal symptoms such as dyspepsia.nnActive components such as carvone and limonene may play a role in these antispasmodic effects by modulating enzyme activity or influencing the release of certain chemicals like prostaglandins, which are known to affect gastrointestinal motility and pain modulation.nn

Usages associés

Digestive spasms

Galactagogue

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Caraway is traditionally used as a galactagogue to stimulate breast milk production. Its components, notably carvone, may promote lactogenic activity by increasing prolactin, a hormone essential for lactation. However, there is no strong clinical evidence supporting this use.nn

Usages associés

Lactation


Safe dosage

Adults aged 10 years and older: 1.5 g - 6 g (seeds)

- Infusion: the caraway fruits (1.5 to 6 g), crushed immediately before use, covered with 150 ml of boiling water and left to steep for 10-15 minutes. - Oil: 50 to 150 mg.

Children aged 4 to 10 years: 1 g - 4 g (seeds)

- Infusion: the caraway fruits (1 to 4 g), crushed immediately before use, covered with 150 ml of boiling water and left to steep for 10-15 minutes.

Child aged 1 to 4 years: 1 g - 2 g (seeds)

- Infusion: caraway fruits (1 to 2 g), crushed immediately before use, covered with 150 ml of boiling water and left to steep for 10-15 minutes.

Infant up to 12 months: 1 g (seeds)

- Infusion: caraway fruits (up to 1 g), crushed immediately before use, covered with 150 ml of boiling water and left to steep for 10-15 minutes.


Precautions

Breastfeeding woman: use with caution

Caraway is used to promote lactation as a herbal tea. However, it is recommended to seek the advice of a healthcare professional before using caraway oil.


Contraindications

Pregnant women: prohibited

Caraway oil may stimulate menstruation.