Brewer's yeast: benefits, dosage, contraindications

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Brewer's yeast is a group of specific yeast strains of Saccharomyces cerevisiae where "saccharo" means sugar, "myces" means fungus, and "cerevisiae": which comes from beer In 1837, yeasts were recognized as living organisms responsible for alcoholic fermentation and reproducing by budding. A little later, Louis Pasteur demonstrated that during the fermentation process, yeasts remain perfectly healthy and can multiply. This fermentation, which converts sugars into alcohol and carbon dioxide, provides the energy necessary for yeasts to live in anaerobiosis (without oxygen). Brewer's yeast is used as a dietary source of minerals and B-complex vitamins (with the exception of B12). Some dietary supplements containing brewer's yeast include dried non-living yeast, while others contain live yeast. Preparations of viable or revivable microorganisms are called "probiotics", while non-living microorganisms are called "postbiotics". Brewer's yeast is one of the most valuable plant-based sources of dietary protein, second only to spirulina (60%), with its 48% protein content. Among the proteins contained in brewer's yeast are glutathione, cysteine, glycine... Yeasts readily assimilate the minerals present in their culture medium. This property has been taken advantage of with the development of yeasts enriched with chromium or selenium. Brewer's yeast is recommended for children and adolescents during periods of growth, for pregnant or breastfeeding women, for vegetarians and vegans, and also for athletes. Because of its rich composition, brewer's yeast is often recommended for the beauty of the skin, hair, and nails.

Family or group: 

Probiotics, Superfood


Indications

Scoring methodology

EFSA approval.

Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with consistently positive conclusions for the indication.
Several randomized, double-blind, controlled clinical trials (> 2), including a significant number of patients (>100), with positive conclusions for the indication.
One or more randomized studies, or several cohorts or epidemiological studies, with positive conclusions for the indication.
Clinical studies exist but are uncontrolled, with conclusions that may be positive or conflicting.
No clinical studies to date that can demonstrate the indication.


Irritable bowel syndrome
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A meta-analysis of the results of two clinical studies shows that daily intake of 500 mg or 1000 mg of the specific brewer's yeast strain CNCM I-3856, standardized to 8 billion colony-forming units (CFU) per gram, for up to 12 weeks, may reduce abdominal pain and discomfort and improve stool consistency in patients with constipation-predominant IBS. It appears that at least one month is required for benefits to manifest. Additional clinical research shows that taking the same product at a dose of 2 billion CFU twice daily in addition to standard treatment for 8 weeks modestly improves abdominal pain and stool consistency compared with standard treatment alone. Benefits were evident within 4 weeks and were observed in patients with diarrhea-predominant, constipation-predominant, and mixed-type IBS.

Posologie

posologieOral

posologie500 - 1000 mg

formulationrevivable yeast, CNCM I-3856


Immune support
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A preliminary clinical study shows that taking a specific preparation of dried, inactive brewer's yeast at a dose of 500 mg per day for 12 weeks reduces the incidence of cold or flu symptoms by 10 to 20% compared with placebo in adults with no history of influenza vaccination. Taking this preparation does not appear to reduce the duration or severity of cold or flu symptoms that occur in these patients. However, in patients recently vaccinated against influenza, clinical research shows that taking this same preparation at a dose of 500 mg per day for 12 weeks reduces the risk of developing cold or flu symptoms by about 11% and reduces the duration of symptoms that develop by 0.85 day compared with placebo.

Posologie

posologieOral

posologie500 mg

formulationYestimun, EpiCor


Athletic performance
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A 13-day study with supplementation of 250 mg of brewer's yeast beta-glucan showed a reduction in certain inflammatory markers following intense exercise. No differences were observed in muscle function or creatine kinase levels between the groups. However, a decrease in myoglobin, a muscle protein released during muscle damage, was noted after 72 hours in the supplemented group. This group also reported an improved mood, with greater vigor and less anger, compared to the placebo group. Note that these results apply to a specific extract providing beta-glucans.

Posologie

posologieOral administration

posologie250 mg

formulationYestimun, revivable yeast, dried yeast


Type 2 diabetes
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Because of its chromium content, brewer's yeast may benefit people with diabetes. Chromium is involved in several physiological processes, including potentiation of insulin receptors and the possible reduction of insulin resistance, improved glucose tolerance, and lowered blood glucose. There is also a hypothesis that brewer's yeast increases insulin release.

Posologie

posologieOral administration

posologie1 g

formulationRevivable yeast, dried yeast


Synergies


Skin health
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Thanks to its richness in B vitamins and particularly vitamins B5, B3, B8 and B2, brewer's yeast may contribute to skin health: - Acne (vitamins B5 and B3) - Wound healing - Dermatoses The use of brewer's yeast, in the form of dietary supplements, for the beauty and health of the skin and appendages (hair, nails) is the best-known indication to the general public. It is recommended to take brewer's yeast supplements for 2 months.

Posologie

posologieOral administration

posologie1 g

duration2 months

formulationre-hydratable yeast, dried yeast


Vegetarian diet
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Thanks to its richness in B vitamins and proteins, brewer's yeast can be a good supplement for vegetarians and vegans.

Posologie

posologieOral administration

posologie1 g

formulationre-hydratable yeast, dried yeast


Acne
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Brewer's yeast is valued for its beneficial effects on the skin, notably due to its richness in vitamins B5 and B3, which are recognized for their effectiveness in fighting acne. These vitamins play a key role in reducing skin inflammation and promoting healthy skin.

Posologie

posologieOral administration

posologie1 g

formulationre-hydratable yeast, dried yeast


Properties


Digestive effect

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Brewer's yeast can increase intestinal disaccharidase, saccharidase, maltase and lactase activity to potentially relieve symptoms of diarrhea. nnIn addition, it specifically activates the PPAR-alpha receptor while inhibiting certain cytokines that promote inflammation. This dual mechanism contributes to analgesic and anti-inflammatory effects in the intestine.nn

Usages associés

Irritable bowel syndrome

Anticancer

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Laboratory research has revealed that brewer's yeast can induce apoptosis, that is, programmed cell death, in digestive system and breast cancer cells. nnIn addition, ergosterol, a component of brewer's yeast, can inhibit the growth of breast cancer cells, particularly those that are estrogen-sensitive, in the presence of estradiol-17β. These findings suggest that brewer's yeast may have therapeutic potential in the fight against certain types of cancer.nn


Immunomodulatory

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There appears to be interest in using brewer's yeast as an immunostimulant and to prevent viral respiratory infections.nnA brewer's yeast-based product derived from Saccharomyces cerevisiae shows significant immunostimulant properties. It activates and mobilizes NK (natural killer) cells and T lymphocytes, which are crucial for immune defense, and increases levels of interferon-gamma, a cytokine essential to the immune response. nnThis activation plays an important role in protection against infections, particularly respiratory viruses such as the common cold and influenza. nn

Usages associés

Immune support

Antibacterial

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Brewer's yeast has antimicrobial properties, acting through the production of compounds such as killer toxins or mycocins, which disrupt the cell membrane of susceptible microorganisms. It is effective against Escherichia coli and Staphylococcus, which cause urinary and skin infections, as well as against Clostridium tyrobutyricum and Clostridium butyricum, which are associated with foodborne illness.


Safe dosage

Adult: 500 mg - 2000 mg

The recommended dose varies by product. Generally 500 mg to 2 g.


Interactions

Médicaments

Monoamine oxidase inhibitor (MAOI): strong interaction

Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs could increase the risk of a hypertensive crisis.

Plantes ou autres actifs

Antifungal: minor interaction

Some brewer's yeast products contain live yeast. Therefore, taking antifungals simultaneously may reduce the benefits of the yeast.


Precautions

Immunodeficiency: avoid

It is generally accepted that people with a weakened immune system have an increased risk of developing a fungal infection when using brewer's yeast. Cases of fungemia caused by Saccharomyces cerevisiae have been observed in severely immunocompromised patients. Therefore, it is advised to use brewer's yeast with caution in these patients.

Pregnant women: use with caution

There are no studies concerning the use of brewer's yeast in pregnant women.

Breastfeeding women: use with caution

There are no studies concerning the use of brewer's yeast in breastfeeding women.


Contraindications

Crohn's disease: contraindicated

Brewer's yeast may increase the severity of Crohn's disease.